Everything about Elastin totally explained
Elastin is a
protein in
connective tissue that's
elastic and allows many tissues in the body to resume their shape after stretching or contracting. Elastin helps skin to return to its original position when it's poked or pinched. Elastin is also an important load-bearing tissue in the bodies of mammals and used in places where mechanical energy is required to be stored.
Composition
It is primarily composed of the
amino acids
glycine,
valine,
alanine, and
proline.
A specialized protein with the weight of 64,000-66,000, it has an irregular or random coil conformation made up of 830 amino acids.
Elastin is made by linking many soluble
tropoelastin protein molecules, in a reaction
catalyzed by
lysyl oxidase, to make a massive insoluble, durable
cross-linked array. The amino acid responsible for these cross-links is
lysine.
Desmosine and
isodesmosine are both found in elastin.
Locations in body
Elastin serves an important function in
arteries and is particularly abundant in large elastic blood vessels such as the
aorta. Elastin is also very important in the
lungs,
elastic ligaments, the
skin, the
bladder,
elastic cartilage, and the
intervertebral disc above the
sacroiliac. It is present in all vertebrates above the jawless fish .
Further Information
Get more info on 'Elastin'.
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